© by Song Laboratory

Jang, S. and Song, J.J. ,The big picture of chromatin biology by Cryo-EM. Current Opinion in Structural Biology (2019)

Jang, S., Kang, C., Yang, H-.S., Jung, T., Hebert, H., Chung, K.Y., Kim, S.J., Hohng, S., Song, J.J., Structrual basis of recognition and destabilization oof histone H2B ubiquitinated nucleosome by DOT1L histone H3 Lys79 methyltransferase. Genes & Development (2019)

Lee, Y.J., Yoon, E.J., Cho, S.H., Schmähling, S., Müller, J., Song, J.J., Structural Basis of MRG15 Mediated-activation of ASH1L Histone Methyltransferase by Reseasing an Auto-inhibitory Loop. Structure (2019)

Schmaehling, S., Meiler, A., Lee, Y., Mohammed, A., Finkl, K., Tauscher, K., Israel, L., Borath, M., Philippou-Massier, J., Blum, H., Habermann, B., Imhof, A., Song, J.J., Mueller, J., Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC. Development (2018)

Yoon, J.M., Kim, S.J., An, S., Leitner, A., Jung, T.Y., Aebersold, R., Hebert, H., Cho, U.-S., Song, J.J., Integrative structural investigation on the architecture of human Importin4_histone H3/H4_Asf1a complex and its histone H3 tail binding. Journal of Molecular Biology (2018). 

An, S*, Yoon, J.M.*, Kim, H., Song, J.J., Cho, U.-S., Structure-based nuclear importin mechanism of histone H3 and H4 mediated by Kap123. eLife (2017) (*Co-first author)

Hyun, K., Noh, Y-.S., Song, J.J., Arabidopsis FRIGIDA stimulates EFS histone H3 Lys 36 methyltransferase activity. Plant Cell Reports (2017).

Kim D., Setiaputra, D., Jung, T.Y., Chung, J., Leitner, A., Yoon, J., Febersold, R., Hebert, H., Yip, C.K., Song, J.J., Molecular Architecture of Yeast Chromatin Assembly Factor 1. Scientific Reports (2016)

Hyun, K., Oh, J.E., Park, J.H., Noh, Y.-S., Song, J.J. Structural Analysis of FRIGIDA Flowering-time Regulator. Molecular Plant (2016)

Lee, Y., Song, J.J., Reconstitution and Crystallization of Sir 3/4 in a Complex with Nucleosome. Bulletin of the Korean Chemical Society (2015).

Yoon, J.H., Jo, M.H., White, E.J.F., De, S., Hafner, M., Zucconi, B.E., Abdelmohsen, K., Martindale, J.L., Yang, X., Wood, W.H., Shin, Y.M., Song, J.J., Tuschl, T., Becker, K.G., Wilson, G.M., Hohng, S., Gorospe, M., AUF1 promotes let-7b loading on Argonaute 2. Genes & Development (2015)

Kang, C., Song, J.J., Lee, J., Kim, M.Y., Epigenetics: An emerging player in gastric cancer. World J. Gastroenterol. (2014)

Jung, S.-R., Kim, E., Hwang, W., Shin, S., Song, J.J.*, Hohng, S.*, Dynamic anchoring of the 3'-end of the guide strand controls the target dissociation of Argonaute-guide complex. J. Am. Chem. Soc. (2013) ( *co-corresponding authors)

Jo, M.H., Shin, S., Jung, S.-R., Kim, E., *Song, J.J., *Hohong, S. Human Argonaute2 has diverse reaction pathways on target RNAs. Molecular Cell (2015) (*co-corresponding authors)

Park, J. Lammers, F., Herr, W., and Song, J.J., HCF-1 self-association via an interdigitated Fn3 structure facilitates transcriptional regulatory complex formation. Proc. Natl. Acad. Sci. U.S.A. (2012)

Cho, J.-N., Ryu, J.-Y., Jeong, Y.-M., Park, J., Song, J.J., Amasino, R.M., Noh, B., and Noh, Y.-S. Control of Seed Germination by Light-Induced Histone Arginine Demethylation Activity. Dev. Cell 22, 1-13 (2012)

Kim, E. and Song, J.J. Diverse ways to be specific:a novel Zn-binding domain confers substrate specificity to UTX/KDM6A histone H3 Lys27 demethylase. Genes & Dev. 25,2223-2226 (2011)

An, S., and Song, J.J., The coded functions of noncoding RNAs for gene regulation. Mol. Cells 31 (2011)

An, S., Yeo, K.J., Jeon, Y.H., and Song, J.J., Crystal structure of human histone methyltransferase

Ash1L catalytic domain and its implications on the regulatory mechanism., J. Bio. Chem. (2011) Cover Article

Zhao, J., Ohsumi, T.K., Kung, J.T., Grau, D.J., Sarma, K., Song, J.J., Kingston, R.E., Borowsky, M., Lee, L.T., Genome-wide identification of Polycomb-Associated RNAs by RIP-seq., Mol. Cell 40, 939-953 (2010)

Zhao, J., Sun, B.K., Erwin, J.A., Song, J.J., Lee, J.T., Polycomb proteins targeted by a short repeat RNA to the mouse X-chromosome. Science 322, 750-756(2008)

Song, J.J., Kingston, R.,E. WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket., J. Biol. Chem. 283, 34258064 (2008)

Song, J.J., Garlick, J.D., Kingston, R.E., Structural basis of Histone recognition by p55, Genes & Dev., 22, 1313-1318 (2008). Cover paper

Song, J.J., Joshua-Tor, L., Argonaute and RNA – getting into the groove. Curr. Opinion Struct. Biol. 16,5-11 (2006).

Rivas, F.V.*, Tolia, N.H.*, Song, J.J.*, Aragon, J.P., Liu, J., Hannon, G.J., Joshua-Tor, L., Purified Argonaute2 and siRNA form recombinant human RISC. Nat. Struct. Mol. Biol. 21, 240-249 (2005). (*contributed equally)

Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J. J., Hammond, S. M., Joshua-Tor, L., Hannon, G.J., Argonaute2 is the catalytic engine of mammalian RNAi, Science 305, 1437-1441(2004).

Song, J. J., Smith, S. K., Hannon, G. J., Joshua-Tor, L., Crystal structure of Argonaute and 

its implications for RISC Slicer activity. Science 305, 1434-1437(2004). Cover Research article

Song, J. J., Liu J., Tolia, N.H., Schneiderman, J., Smith, S.K., Martienssen, R.A., Hannon, G.J., Joshua-Tor, L., The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes, Nat. Struct. Biol. 10, 1026-1032(2003).